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Dna 2 - College Paper

Dna 2


In the last 10 years, there has been some scientific leaps concerning diabetes, and genetic engineering. The increasing incidence and diagnostic detection of diabetes worldwide coupled with changing trends in the food animal market stimulated people to seek alternative sources of insulin completely independent of an animal-gland source. (Ryan, 1986). The basic recombinant DNA process of formulating insulin was developed. DNA carries the genetic information that determines the fate of each cell. Recombinant DNA technology allows manipulation of bacterial host cells by insertion of genes for production of either the A chain or the B chain of the insulin molecule, or the entire proinsulin ...

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proinsulin. The genetic coding for human proinsulin is inserted into the special E. coli bacteria which are then grown in a fermentation process to produce human proinsulin. With genetic engineering, new proteins are synthesized. They can be introduced into plants or animal genomes, producing a new type of disease resistant plants, capable of living in inhospitable environments. When introduced into bacteria, these proteins have also produced new antibiotics and useful drugs. Techniques of cloning generate large quantities of pure human proteins, which are used to treat diseases like diabetes. In the future, a resource bank for rare human proteins or other molecules is a possibility. For instance, DNA sequences which are modified to correct a mutation, to increase the production of a specific protein or to produce a new type of protein can be stored. This technique will probably play a key role in gene therapy. (Stwertka, 1982)
The insulin hormone is essential for a healthy and ...

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A large amount of water is needed to dissolve the excess sugar, resulting in excessive thirst and urination. Without glucose for energy, the body begins to metabolize protein and fat. Fat metabolism results in the production ketones in the liver. Ketones are excreted in the urine along with sodium bicarbonate, which results in a decrease in the pH of the blood. This condition is called acidosis. To correct acidosis, the body begins a deep, labored respiration, called Kussmaul's respiration. Left unchecked, a person in this situation will fall into a coma and die. (What is Insulin, 1998)
Insulin is produced by the pancreas that controls the level of sugar (glucose) in the blood and is ...

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PAPER DETAILS
Added: 6/14/2004 03:34:44 AM
Category: Science & Nature
Type: Premium Paper
Words: 1906
Pages: 7

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