Von Willebrand�s Disease
Blood is carried throughout the body within a network of blood vessels. When our tissues are injured (cut on skin), are blood vessel is disrupted, and we bleed through the holes in the blood vessel wall. Normally, we stop bleeding through two integrated processes, or the formation of a platelet plug and the formation of a blood clot, this is called hemostasis. You may not know it, but there is a protein in or blood called the von Willebrand factor (vWF), which causes the platelets to bind to the bleeding blood vessel wall. These adherent platelets activate other platelets to clump at the hole on the blood vessel wall, this stops the bleeding. Now if you have an absent on the von Willebrand ...
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properly when blood vessels are injured, therefor it takes longer for a blood clot to form. In some patients, the factor VIII (the anti-hemophilic factor that helps blood clot) is also reduced, and blood clotting is severally impaired. In patients with hemophilia, the primary problem is the decrease or absents the factor VIII, while the von Willebrand factor is normal.
Erik von Willebrand, who lived in Helsinki, Finland, founded in 1924. Who described a new type of bleeding disorder in the inhabitants of the �land Islands is the Gulf of Bothnia, which is located between Sweden and Finland. This disorder was found to affect both males and females, and the symptoms were usually mild with bleeding from nose, mouth, or intestinal tract. Bruising is the primary problem in , rather than muscle or joint bleeding which occurs with hemophilia. Vascular, pseudohemophila, angiohemophilia, Minot-von Willebrand disease, constitutional thrombopathy, and Willebrand-Juergens disease are older ...
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do not recall how they got them, older children and adults who bruise frequently without knowing how they got it may have von Willebrand�s disease. Since von Willebrand factor increase during pregnancy, bleeding at delivery is relatively uncommon except in patients with the absents of von Willebrand factor or in those who have an abnormally functioning molecule.
Symptoms are high variable, even in patients within the same family. Most people with this disorder have varied mild symptoms, and many of these are undiagnosed unless a family member is identified or testing is performed. However, in other individual, life-threatening bleeding may occur after extensive injuries or operations. ...
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Von Willebrand�s Disease. (2005, January 10). Retrieved November 28, 2024, from http://www.essayworld.com/essays/Von-Willebrands-Disease/20343
"Von Willebrand�s Disease." Essayworld.com. Essayworld.com, 10 Jan. 2005. Web. 28 Nov. 2024. <http://www.essayworld.com/essays/Von-Willebrands-Disease/20343>
"Von Willebrand�s Disease." Essayworld.com. January 10, 2005. Accessed November 28, 2024. http://www.essayworld.com/essays/Von-Willebrands-Disease/20343.
"Von Willebrand�s Disease." Essayworld.com. January 10, 2005. Accessed November 28, 2024. http://www.essayworld.com/essays/Von-Willebrands-Disease/20343.
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